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SARS-Cov-2 & Fuluwenza A&B Combo Rapid Test Cassette (swab)

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Mankhwala Mwatsatanetsatane

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Colonaviruses yatsopano ndi ya β genus.COVID-19 ndi matenda opatsirana opatsirana kwambiri. Anthu nthawi zambiri amakhala pachiwopsezo. Pakadali pano, odwala omwe ali ndi kachilombo ka coronavirus ndiye gwero lalikulu la matenda; Anthu omwe ali ndi kachilombo ka HIV angakhale kachilombo koyambitsa matenda. Kutengera ndikufufuza kwamatenda apano, nthawi yolumikizira ndi masiku 1 mpaka 14, makamaka masiku 3 mpaka 7. Akuluakulu mawonetseredwe monga malungo, kutopa ndi chifuwa youma.

Kuchulukana kwa mphuno, kuthamanga kwa mphuno, zilonda zapakhosi, myalgia ndi kutsekula m'mimba kumapezeka m'matenda angapo. Fuluwenza (yemwe amadziwika kuti 'chimfine') ndimatenda opatsirana kwambiri, opatsirana a m'mapapo. Matenda a chimfine amapezeka chaka chilichonse m'nyengo yogwa komanso m'nyengo yozizira. Matenda a mtundu wa A amakhala ofala kwambiri kuposa ma virus a mtundu wa B ndipo amapezeka ndi miliri yoopsa ya fuluwenza, pomwe matenda amtundu wa B nthawi zambiri amakhala ocheperako. Miyezo ya golide yodziwitsira labotale ndi masiku 14 am'maselo achikhalidwe omwe ali ndi mitundu ingapo yama cell yomwe ingathandizire kukula kwa fuluwenza ya virus. .Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) ndi njira yatsopano yomwe ili yovuta kwambiri kuposa chikhalidwe chodziwika bwino pazikhalidwe za 2-23% .Komabe, RT-PCR ndiyokwera mtengo, yovuta ndipo iyenera kuchitidwa muma laboratories apadera Chipangizo cha Fluenza A&B Rapid Test chimazindikira bwino kupezeka kwa antigen Fluenza A ndi / kapena Fluenza B antigen mu nasalswab kapena khosi swab kapena ma nasal aspirate specimens, zomwe zimapereka zotsatira mkati mwa mphindi 15. Fuluwenza A ndi Fuluwenza B antigen m'matumbo am'mimbamo, pakhosi kapena m'mphuno.

MFUNDO

Novel Coronavirus (SARS-Cov-2) Antigen Rapid Test ndi immunochromatographic membrane assay yomwe imagwiritsa ntchito ma anti-monoclonal antibodies ku Novel coroinavirus. Chipangizochi chimapangidwa ndi magawo atatu otsatirawa, omwe ndi sampuli pad, reagent pad ndi reaction membrane. Mzere wonse wakhazikika mkati mwa chipangizo cha pulasitiki. Kakhungu ka reagent kamakhala ndi colloidal-golide wolumikizidwa ndi ma monoclonal antibodies motsutsana ndi Novel coroinavirus; nembanemba yomwe imagwira ili ndi ma antibodies achiwiri a Novel coroinavirus, ndi ma polyclonal antibodies olimbana ndi mbewa ya globulin, yomwe isanachitike. Zowonjezeredwa muwindo lazenera, ma conjugates owuma mu reagent pad amasungunuka ndikusunthira limodzi ndi chitsanzocho. Ngati Novel coroinavirus ilipo mchitsanzo, zovuta zomwe zimapangidwa pakati pa anti-Novel coroinavirus conjugate ndipo kachilomboka kadzagwidwa ndi antiNovel coroinavirus monoclonal yokutidwa m'chigawo cha T. Kaya chitsanzocho chili ndi kachilomboka kapena ayi, yankho likupitabe patsogolo kukakumana ndi reagent ina (anti-mbewa IgG antibody) yomwe imamanga ma conjugates otsala, potero imapanga mzere wofiira m'chigawo cha C.

Novel Coronavirus (SARS-Cov-2) Antigen Rapid Test Cassette (swab) mankhwala amatha kudziwa SARS-Cov-2 nucleo-protein (makamaka) ndi spike protein. Oposa 90% antibody omwe amagwiritsidwa ntchito mu Novel Coronavirus (SARS-Cov-2) ) Antigen Rapid Test Cassette (swab) ndi anti-nucleoprotein ya SARS-Cov-2 ndipo chandamale cha protein ndi SARS-Cov-2 nucleoprotein.

Asirikali otsala omwe amagwiritsidwa ntchito mu Novel Coronavirus (SARS-Cov-2) Antigen Rapid Test Cassette (swab) ndi anti-Spike protein ndipo chandamale chake ndi SARS-Cov-2 Chidutswa chokhazikika cha Spike protein.

Pakadali pano, kaya ndi N501Y ku United Kingdom kapena 501Y.V2 ku South Africa, zidutswa zosiyanasiyananso ndi kachidutswa ka RBD ka protein ya S, ndi zidutswa za ma antibodies omwe amagwiritsidwa ntchito mu Novel Coronavirus (SARS-Cov-2) Antigen Rapid Test Cassette (swab) sinasinthidwe. Chifukwa chake, Novel Coronavirus (SARS-Cov-2) Antigen Rapid Test Cassette (swab) imatha kuzindikira mitundu ya SARS-Cov-2.

Chifukwa chake, Novel Coronavirus (SARS-Cov-2) Antigen Rapid Test Cassette (swab) imatha kuzindikira molondola ma protein a protein ndi spike amitundu ya SARS-Cov-2. Influenza A & B Rapid Test ndiyabwino, yoyenda motsatizana immunoassay pozindikira Fluenza A ndi Fluenza B nucleoproteins mu mphuno, khosi kapena khosi la aspirate. Pachiyesochi, antibody wodziwika ndi Fluenza A ndi Fluenza B nucleoproteins ndi

Poyesedwa, zojambulazo zimayankhidwa ndi anti-Influenza A ndi / kapena Fluenza B yomwe imakutidwa ndi tinthu tating'onoting'ono. Kusakanikirana kumakoka nembanemba kuti igwire ntchito ndi anti-Influenza A ndi / kapena Fuluwenza B pa nembanemba ndikupanga mzere umodzi kapena iwiri yamitundu m'mayeso oyesera. Kukhalapo kwa mzere wachikuda m'maboma onse awiri kapena awiriwa kumawonetsa zotsatira zabwino. Kuti ikhale ngati njira yoyendetsera, mzere wachikuda nthawi zonse muziwoneka m'dera loyang'anira ngati mayeso achita bwino.

KUSANTHULA KWAMBIRI NDIPONSO KUKONZEKERETSA

1. Zosonkhanitsa:

Ikugwiritsidwa ntchito pozindikira kachilombo ka Novel coroinavirus kapena Influenza A & B kuchokera pazitsanzo za Nasopharyngeal swab. Gwiritsani ntchito zitsanzo zomwe mwazipeza kumene kuti muchite bwino. Kusonkhanitsa zitsanzo zosakwanira kapena kutengera zitsanzo zosayenera kumatha kubweretsa zotsatira zabodza. Kwathunthu ikani cholembera chosawilitsidwa chomwe chimaperekedwa mu chida ichi mu beseni la nasal, ndikusambira kangapo kuti mutenge ma cell a epidermal a mamina. Ndikulimbikitsidwa kuti mutenge zitsanzo kuchokera ku Nasopharyngeal kuti mupeze zotsatira zolondola.

2. Kukonzekera kwa fanizo:

1) Tulutsani botolo limodzi la Zitsanzo Zofukula Zotsitsa, chotsani botolo la botolo, onjezerani chomenyera chilichonse mu chubu.

2) Kuphulika Kwa Nasopharyngeal

Ikani swab mu chubu chojambulira chomwe chili ndi Zitsanzo Zofukula Zitsanzo. Sinthirani swab mkati mwa chubu pogwiritsa ntchito zozungulira mozungulira mbali ya chubu kuti madzi amveke ndikubwezeretsanso ku swab, chotsani swab. Yankho lotulutsidwa lidzagwiritsidwa ntchito ngati mayeso.

Mayendedwe oti mugwiritse ntchito

Lolani mayeso, choyimira, cholumikizira chotsitsa kuti chikhale chofanana ndi kutentha kwapakati (15-30 ° C) musanayesedwe.

1.Chotsani chida choyesera kuchokera mu thumba lojambulidwa losindikizidwa ndikuligwiritsa ntchito posachedwa. Ikani chida choyesera pamalo oyera komanso osalala. Zotsatira zabwino kwambiri zidzapezeka ngati kuyesa kumachitika atangotsegula thumba la zojambulazo.

2. Tulutsani Chidebe Chokumbiramo.

3. Tulutsani botolo limodzi la Zitsanzo Zofukula Zotchinga, chotsani kapu ya botolo, onjezerani chotsitsa chonse mu chubu chowonjezera. 4. Ikani chojambulira cha swab chojambulira muzitsulo zowonjezera. Sinthirani swab kwa masekondi pafupifupi 10 kwinaku mukugwedeza mutu mkati mwa chubu kuti mutulutse antigen mu swab.

5.Chotsani swab yolera yotseketsa kwinaku mukufinya mutu wosawilitsidwa pakati pa Buffer mukamachotsa kuti mutulutse madzi ambiri momwe mungathere. Tayani swab yolera yotseketsa molingana ndi pulogalamu yanu yotaya zinyalala.

6. Pukutani ndi kumangitsa Nozzle ndi Sefani pa chubu chosonkhanitsira, kenako sinthani chubu chojambuliracho mwamphamvu kuti musakanize mtunduwo ndi choyikapo chotengera. Onani fanizo.

7. Onjezerani madontho atatu a yankho (pafupifupi 80ul) pachitsanzo chilichonse ndikuyamba nthawi. Werengani zotsatirazo kwa mphindi 10 ~ 20. Osatanthauzira zotsatira pambuyo pa mphindi 20.

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KUMASULIRA ZOTSATIRA

ZABWINO SARS-Cov-2: Kuonekera mizere iwiri yofiira. Mzere umodzi wofiira umapezeka m'dera lolamulira (C), ndi mzere umodzi wofiira mdera loyesa (T).

Fuluwenza Yabwino: Mizere iwiri yamitundu yosiyana imawonekera. Mzere umodzi wachikuda uyenera kukhala m'dera loyang'anira (C) ndipo mzere wina wachikuda uyenera kukhala m'dera la Fuluwenza A (A). Zotsatira zabwino m'dera la Fuluwenza A zikuwonetsa kuti antigen Fluenza A idapezeka mchitsanzo.

Fluenza Yabwino B: Mizere iwiri yamitundu yosiyana imawonekera. Mzere umodzi wachikuda uyenera kukhala m'dera loyang'anira (C) ndipo mzere wina wachikuda uyenera kukhala m'dera la Fluenza B (B). Zotsatira zabwino m'dera la Fluenza B zikuwonetsa kuti antigenenza ya Flu B idapezeka mchitsanzo.

Fuluwenza WABWINO A ndi Fuluwenza B: Mizere itatu yamitundu yosiyana imawonekera. Mzere umodzi wachikuda uyenera kukhala m'dera loyang'anira (C) ndipo mizere iwiri yoyera iyenera kukhala m'dera la Fuluwenza A (A) ndi Fluenza B (B) Zotsatira zabwino m'dera la Fuluwenza A ndi dera la Fluenza B zikuwonetsa kuti Fuluwenza A antigen ndi antigen Fluenza B adapezeka muchitsanzo.

*ZINDIKIRANI: Mthunzi wautundu umatha kusiyanasiyana, koma uyenera kuganiziridwa kuti ndiwothandiza paliponse pomwe pali mzere wolowerera.

ZOIPAMzere umodzi wokha wofiira umapezeka mdera lolamulira (C), ndipo palibe mzere m'chigawo choyesera (T / A / B).

Zosayenera: Palibe mzere wofiira womwe ukuwoneka m'dera lolamulira (C). Mayesowa ndi osavomerezeka ngakhale pali mzere pagawo loyesa (T / A / B). Mavoliyumu osakwanira kapena njira zolakwika panjira ndiye zifukwa zazikulu zolepheretsa mzere kulamulira. Onaninso njira yoyeserera ndikubwereza mayesowo pogwiritsa ntchito chida chatsopano choyesera. Ngati vutolo likupitilira, siyani kugwiritsa ntchito zida zoyeserera mwachangu ndikulumikizana ndi omwe amagawa nawo pafupi.


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